Peptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2기계 학습과 결합된 펩티드 마이크로어레이는 SARS-CoV-2에 대한 중화 기능을 가진 인간 항체 반응의 개별 에피토프를 나타냅니다.Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료법, [키워드] anti-SARS-CoV-2 antibody Antibody binding assays binding epitope capture causative agent cellular coronavirus coronavirus SARS-CoV-2 Course COVID-19 detectable epitope Epitopes human antibody response IgA IgG IgM antibody immunoassays incubated infected with SARS-CoV-2 machine learning Microarray N-terminus negative control samples neutralization neutralization assays Neutralizing Neutralizing antibodies nine overlapping Patient peptide peptide arrays peptides positive protective effect Protective effects random Random forest response S protein SARS CoV SARS CoV-2 SARS-CoV-2 sera serology Serology. Specific structural protein structural proteins the disease the S protein vaccine candidate vaccine candidates Viral [DOI] 10.1080/22221751.2022.2057874 PMC 바로가기 [Article Type] Article
Recent advances in applying G-quadruplex for SARS-CoV-2 targeting and diagnosis: A reviewArticle Published on 2022-11-302022-11-15 Journal: International journal of biological macromolecules [Category] SARS, 변종, 치료기술, 치료제, [키워드] accumulating addressed antiviral drug Care caused coronavirus SARS-CoV-2 diagnostic functions G-quadruplex Health Host Immune escape Intervention Ligand ligands neutralizing antibody nucleic acid pandemic polymerases protease Protein question recent regulate SARS-CoV-2 SARS-CoV-2 detection Structure targeting Targeting. Treatment strategies Vaccine variant virus virus [DOI] 10.1016/j.ijbiomac.2022.09.152 PMC 바로가기
Antiviral efficacy of cerium oxide nanoparticlesArticle Published on 2022-11-052022-11-15 Journal: Scientific Reports [Category] SARS, 치료제, [키워드] Antiviral antiviral activity antiviral efficacy candidate Concentration coronavirus SARS-CoV-2 cytotoxicity decrease Effect Efficacy evidenced expected gastroenteritis highest Influenza virus Ion mechanism MS2 bacteriophage Nanomaterial no decrease non-enveloped virus nonspecific plaque forming unit Registered released sensitivity significantly lower tested virus virus viruses were assessed [DOI] 10.1038/s41598-022-23465-6 PMC 바로가기
Severe COVID-19 increases the risk of schizophreniaShort communication Published on 2022-11-012022-10-05 Journal: Psychiatry research [Category] SARS, 유전자 메커니즘, [키워드] Analysis Central nervous system coronavirus SARS-CoV-2 COVID-19 COVID-19 patients Effect Genetic hospitalized COVID-19 increase increased risk indicated mendelian randomization mental health performed risk SARS-COV-2 infection Schizophrenia [DOI] 10.1016/j.psychres.2022.114809 [Article Type] Short communication
Evaluation of five immunoassays and one lateral flow immunochromatography for anti-SARS-CoV-2 antibodies detectionArticle Published on 2022-11-012022-11-15 Journal: Enfermedades infecciosas y microbiologia clinica ( [Category] SARS, 진단, 치료기술, [키워드] addition anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody approach caused CLIA CLIA assays Clinical practice complementary coronavirus SARS-CoV-2 COVID-19 COVID-19 patient criteria diagnostic ELISA English evaluated FIVE greater healthcare worker healthy IgG IgM IgM antibody immunoassay immunochromatographic test immunochromatography Inmunocromatografía involved lateral flow Pandemia pandemic para performed Rapid test ROC ROC curves RT-PCR SARS-CoV-2 SARS-CoV-2 coronavirus sensitivity Serología. serological serology serum sample Sin Spanish specificity Support Vaccine [DOI] 10.1016/j.eimce.2020.12.007 PMC 바로가기
The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia FormationArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome appear assays catalytic caused Cell cell-cell fusion cell-cell fusion assay cells cellular cellular component cellular membrane contribute coronavirus coronavirus coronavirus SARS-CoV-2 Coronaviruses COVID-19 COVID-19 pandemic dead defend Defense Efficiency ENhance entry of SARS-CoV-2 examined Formation genetic knockout global public health host cell membranes IFITM IFITMs in viral include Infection inhibiting inhibitory activity innate immune innate immune response Integral interact Interaction interfere intrinsic knockdown lentivirus maturation mechanism membrane membrane protein MHV mouse hepatitis virus nuclear overexpression pandemic Plaque assay precursor prelamin A Prevent protease Proteases PROTECT Protective protective role Protein proteolytic proteolytic activity reduce required restriction factor restriction factor. SARS-CoV-2 SARS-CoV-2 pseudovirus infection shown spike Therapeutic benefit transmembrane protein viral infection viral infections virus virus entry viruses wild-type ZMPSTE24 [DOI] 10.1128/mbio.02543-22 PMC 바로가기
Vaccine hesitancy for coronavirus SARS-CoV-2 in Varanasi IndiaArticle Published on 2022-10-052022-11-15 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] age association conducted coronavirus coronavirus SARS-CoV-2 COVID-19 creating detect Factor Factors Frequency Gender Government Government of India help India medium MOST North North India overcome participated proportion Region reported SARS-CoV-2 second wave vaccinate vaccination Vaccine Vaccine hesitancy vaccine hesitancy. Varanasi variant variants virus [DOI] 10.3389/fpubh.2022.892584 PMC 바로가기
Post-COVID-19 psychosis: Cotard’s syndrome and potentially high risk of harm and self-harm in a first-onset acute and transient psychotic disorder after resolution of COVID-19 pneumoniaReview Published on 2022-10-012023-07-07 Journal: Early intervention in psychiatry [Category] COVID19(2023년), [키워드] coronavirus SARS-CoV-2 Cotard's Syndrome first-onset psychosis post-COVID-19 psychosis. [DOI] 10.1111/eip.13254 PMC 바로가기 [Article Type] Review
Clinical studies of detecting COVID-19 from exhaled breath with electronic noseArticle Published on 2022-09-262022-11-15 Journal: Scientific Reports [Category] SARS, 치료기술, [키워드] Accuracy affecting Analysis breath can be used clinical continuous monitoring coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic detect diagnostic methods exploratory gold standard help hospital limit Local metabolism Non-invasive Numerous pandemic Patient PCR point-of-care test polymerase chain problem reported Research Schools spread of COVID-19 Treatment viral infections virus infection VoC VOCs [DOI] 10.1038/s41598-022-20534-8 PMC 바로가기
The impact of COVID-19 lockdown on children with recurrent wheezing and asthma in SpainArticle Published on 2022-09-012022-11-15 Journal: Journal of paediatrics and child health [Category] COVID19(2023년), SARS, 진단, [키워드] age analysed anti-asthmatic agent Asthma asthma. asthmatic Care children coronavirus SARS-CoV-2 country COVID COVID-19 Determination drastic enrolled First wave Hospital admission IgG implementation Laboratory testing lockdown males measure modify MOST National no difference Older Patient positive questionnaire remained required respiratory disorders SARS-CoV-2 SARS-CoV-2 IgG significant increase Spain Spread tested Treatment underlying disease was performed wheezing [DOI] 10.1111/jpc.16068 PMC 바로가기